Hamilton(Leading Global Manufacturer for Laboratory Automation Technology) and Bionano Genomics (Provider of Genome Analysis Solutions)Announced World’s First Ultra High Molecular Weight DNA Extraction Automation Solution for OGM

On June 9, 2022,- Hamilton and Bionano Genomics, Inc. announced the combined development of the Long String VANTAGE to extract Ultra High Molecular Weight (UHMW) DNA for usage in optical genome mapping (OGM). Isolating UHMW DNA of high quantity and quality is an important requirement and the first step in Bionano’s sample preparation roadmap. UHMW DNA extraction is usually performed physically by highly experienced and trained laboratory personnel, thus limiting application and volume in routine sample preparation.

By merging Hamilton’s established knowledge in automating genomic workflows via precision engineering of automated liquid handling solutions and consumables, and Bionano’sexpertise in extraction, enzymatic treatment, and analysis of UHMW DNA molecules, the firms have advanced the world’s first walk-away automation solution for UHMW DNA extraction. The companies have plans to collaborate with hand-picked clinical research laboratories to examine and further develop applications for the usage of the Long String VANTAGE as well as the Bionano Prep SP kits and antedate commercial release of a few of these workflows by the 2022 end.

This partnership has resulted in outstanding outcomes. They have shown an extraordinary ability to expand workflows through the automation of UHMW DNA isolation, which reliably results in enormously long and pure DNA molecules that are appropriate for usage in OGM. This innovation is expected to significantly decrease time to results, lessen hands-on time and enhance OGM performance by standardizing the procedure of UHMW DNA isolation. Hamilton and Bionano are looking forward to seeing customers adopt the Long String VANTAGE solution.